Penicillin inhibits the transpeptidase enzymes (also known as penicillin-binding proteins or PBPs) that cross-link the peptidoglycan chains, which are essential for the structural integrity of the bacterial cell wall. This weakens the wall, leading to cell lysis (bursting) due to osmotic pressure.
Antibiotic such as penicillin blocks
Asked in UPSC CDS 2 2020 · Topic: Bacterial Diseases (Antibiotics: Classification, mechanisms of action, antibiotic resistance)
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