The correct answer is: A. Open a new database.

When you press Ctrl+N in Access, it will open a new database. This is a blank database that you can use to create your own tables, queries, forms, and reports.

Option B is incorrect because Ctrl+O opens an existing database.

Option C is incorrect because Ctrl+W closes the current database.

Option D is incorrect because Ctrl+N does not do any of the things listed in the other options.