- An element is defined by the number of protons in the nucleus, which is its atomic number (Z). All atoms of a given element have the same number of protons. - The mass number (A) of an atom is the total number of protons and neutrons in the nucleus (A = Z + N, where N is the number of neutrons). - Isotopes are atoms of the same element (same Z) but with different mass numbers (different A). - Since Z is the same for isotopes, a different mass number A must be due to a different number of neutrons N. - The number of electrons in a neutral atom is equal to the number of protons (Z). While ions of isotopes can have different numbers of electrons, the definition of isotopes refers to the atomic nucleus.