The film "Paa" features a character with Hutchinson–Gilford progeria syndrome (HGPS), commonly known as Progeria. This is an extremely rare genetic disorder causing affected children to age rapidly from early childhood. Symptoms include growth failure, hair loss, aged-looking skin, joint abnormalities, and cardiovascular problems, leading to a significantly reduced lifespan. Conn's syndrome involves excess aldosterone. Acromegaly involves excess growth hormone in adulthood. Down's syndrome is a chromosomal disorder causing intellectual disability and characteristic physical features. None of these describe the premature aging shown in the film.
Paa is a 2009 Indian comedy-drama film directed by R. Balakrishnan in which Amitabh Bachchan is shown to suffer with a rare genetic disease of childhood characterized by dramatic, premature ageing. What is this type of disorder called ?
Asked in PPSC CS Prelims 2013 · Topic: Genetic Disorders (Definition and Classification of Genetic Disorders)
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