- Zidovudine (AZT) is a nucleoside analog reverse- transcriptase inhibitor (NRTI). - It works by interfering with the reverse transcriptase enzyme that HIV uses to replicate its genetic material. - Although resistance and side effects led to its use primarily in combination therapies later, it was the most widely tried and significant early drug.
The drug most widely tried against AIDS virus is
Asked in JPSC CS Prelims 2011 · Topic: Diseases and Treatment (Principles of Disease Treatment: Pharmacology (Antibiotics, Antivirals, Antifungals))
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