- UV Disinfection Ultraviolet (UV) disinfection is a method used to inactivate pathogenic microorganisms in water by exposing them to UV light. - Water Thickness The effectiveness of UV disinfection is dependent on the depth of water the UV rays need to penetrate. A thinner layer allows for maximum UV exposure. - Standard Thickness The commonly accepted maximum thickness of water for effective UV disinfection is 8 cm (approximately 3 inches).