The correct answer is C. 1504 AD.

Leonardo da Vinci began painting the Mona Lisa in 1504 and worked on it intermittently until his death in 1519. The painting is a half-length portrait of a woman whose expression is both enigmatic and alluring. The Mona Lisa is one of the most famous paintings in the world and is considered to be a masterpiece of Renaissance art.

Option A is incorrect because Leonardo da Vinci was born in 1452.

Option B is incorrect because the Mona Lisa was not painted in 1492.

Option D is incorrect because the Mona Lisa was not painted in 1556.