With reference to normal human beings consider the following statements: In response to the presence of HCL, secretian is produced from the duodenum Enterogastrone is produced in the small intestine in response to the presence of fatty acids Which of these statements is/are correct?

- Statement 1 is correct. Secretin is a hormone produced by S cells located in the lining of the duodenum (the first part of the small intestine). Its secretion is stimulated by the presence of acidic chyme (containing HCl from the stomach) entering the duodenum. Secretin primarily acts on the pancreas, stimulating the release of bicarbonate-rich pancreatic juice, which helps neutralize the acid in the duodenum. - Statement 2 is correct. Enterogastrone is a historical term used to describe any hormone secreted by the duodenal or jejunal mucosa in response to the presence of fat or other substances, which inhibits gastric secretion and motility. Key hormones that function as enterogastrones include Cholecystokinin (CCK) and Glucose- dependent Insulinotropic Peptide (GIP). CCK is produced by I cells in the duodenum and jejunum in response to the presence of fatty acids and amino acids and acts to slow gastric emptying and inhibit gastric acid secretion. Therefore, the statement that enterogastrone (represented by hormones like CCK) is produced in the small intestine in response to fatty acids is correct.