- Statement 1 is correct. Recombinant vector vaccines are developed using genetic engineering techniques. A gene from the target pathogen (e.g., the spike protein gene of SARS-CoV-2) is inserted into the genome of a harmless vector organism (usually a virus or bacterium). This process involves genetic manipulation. - Statement 2 is correct. Both viruses (e.g., adenoviruses, vaccinia virus) and bacteria (e.g., attenuated Salmonella, Listeria) are used as vectors in the development of recombinant vector vaccines. The vector delivers the pathogen's genetic material into host cells to trigger an immune response.
With reference to recent developments regarding Recombinant Vector Vaccines, consider the following statements: Genetic engineering is applied in the development of these vaccines. Bacteria and viruses are used as vectors. Which of the statements given above is/are correct?
Asked in UPSC IAS 2021 · Topic: Genetic Engineering and Biotechnology (Applications in Healthcare: Gene Therapy, Recombinant Vaccines, Molecular Diagnostics)
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