This question matches biological theories and concepts with the scientists associated with them. I. Theory of Mutation: Proposed by Hugo de Vries (D), based on his work with evening primroses. II. Theory of Evolution (by natural selection): Most famously articulated by Charles Darwin (C). III. One gene one enzyme hypothesis: Proposed by George Beadle and Edward Tatum (A), based on their experiments with Neurospora crassa, stating that each gene codes for a specific enzyme. IV. Operon concept: Proposed by François Jacob and Jacques Monod (B) in 1961, explaining the regulation of gene expression in bacteria, particularly the lac operon. Matching these gives: I-D, II-C, III-A, IV-B.