- Thiamine (Vitamin B1) deficiency causes Beri beri, a disease affecting the nervous system (polyneuritis) and cardiovascular system. - Niacin (Vitamin B3) is also known as Nicotinic acid or Nicotinamide. Its deficiency causes Pellagra, characterized by symptoms often referred to as the "4 Ds": dermatitis, diarrhea, dementia, and potentially death. - Riboflavin (Vitamin B2) deficiency leads to ariboflavinosis, symptoms of which include Cheilosis (cracking of the lips and corners of the mouth) and Glossitis (inflammation of the tongue). - Biotin (Vitamin B7) is also known as Coenzyme R. Deficiency is rare but can cause skin conditions, hair loss, and neurological symptoms like hyperesthesia (increased sensitivity). - Cyanocobalamin (Vitamin B12) is essential for DNA synthesis and nerve function. Deficiency causes megaloblastic anemia, specifically pernicious anaemia when absorption is impaired (related to "antipernic factor" intrinsic factor).
Match the following: I II III (1) Thiamine (a) Cheilosis (i) Pellagra (b) Polyneur‐ (2) Niacin (ii) Glossitis itis (c) Nicotin‐ (3) Riboflavin (iii) Beri beri amide (d) Antiper‐ (iv) Hyperes‐ (4) Biotin nic theria (5) Cyanacobal‐ (e) Coen‐ (v) Pernicious amine zyme R anaemia
Asked in TNPSC CS Prelims 2015 · Topic: Vitamins and Nutrition (Water-soluble Vitamins (B-complex, C): Chemical names, sources, functions, deficiency diseases, coenzyme roles)
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Answer: B. (1) – (b) – (iii) (2) – (c) – (i) (3) – (a) – (ii) (4) – (e) – (iv) (5) – (d) – (v)
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