Fischer projections represent molecules in a specific orientation equivalent to an eclipsed conformation, where substituent groups on adjacent carbon atoms are aligned. Eclipsed conformations are generally higher in energy and less stable than staggered conformations due to torsional strain. The most stable conformation for a molecule is usually a staggered conformation (specifically, anti-staggered when possible), not the eclipsed conformation depicted by a Fischer projection.
Which one of the following statements is not correct?
Asked in UPSC CDS 1 2019 · Topic: Organic Chemistry (Stereochemistry: Chirality, optical isomerism, enantiomers, diastereomers, meso compounds, conformational analysis, geometric isomerism.)
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Answer: C. Fischer projection of the molecule is its most stable conformation.
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